Beef and Spinach Stuffed Manicotti

If you love hearty Italian dishes that combine rich flavors with nutritious greens, then this Beef and Spinach Stuffed Manicotti is going to become your new favorite dinner go-to. Tender pasta shells filled with a savory mixture of ground beef, fresh spinach, and creamy cheeses, all baked in a luscious marinara sauce—this dish is pure comfort food at its finest. Whether you’re cooking for family, hosting friends, or simply craving a satisfying meal, this recipe delivers classic taste with an easy, fuss-free method. Get ready to treat yourself to a dinner that’s both indulgent and nourishing!

Why It Deserves a Spot

This Beef and Spinach Stuffed Manicotti deserves a prime spot in your kitchen repertoire because it strikes the perfect balance between indulgence and healthfulness. The combination of lean ground beef and fresh spinach packs in protein and vitamins, while the ricotta and mozzarella bring creamy richness without overpowering the fresh flavors. Not to mention, the Italian seasoning and garlic infuse the filling with mouthwatering aromas that fill your home as it bakes.

Even better, this dish is versatile and approachable for cooks of all skill levels. From prepping the filling to stuffing each manicotti shell, the steps are straightforward and rewarding. Plus, it’s a wonderful make-ahead meal that reheats beautifully for busy weeknights or casual gatherings. If you’ve enjoyed recipes like The Best Homemade Lasagna Recipe or crave that satisfying baked pasta feel, this recipe offers a similar experience with a fresh twist that’s perfect for any occasion.

The Essentials

• 12 manicotti shells – cooked al dente and ready to stuff
• 1 pound ground beef – choose lean for a lighter dish
• 2 cups fresh spinach, chopped – adds vibrant color and nutrition
• 1 cup ricotta cheese – creamy base for the filling
• 1 cup shredded mozzarella cheese – melts beautifully for gooey goodness
• 1/2 cup grated Parmesan cheese – for sharp, nutty flavor
• 2 cups marinara sauce – store-bought or homemade for best results
• 2 cloves garlic, minced – aromatic and flavorful
• 1 teaspoon Italian seasoning – blend of herbs to brighten the filling
• Salt and pepper to taste
• Olive oil – for sautéing and richness

Equipment & Tools

• Large pot – to boil manicotti shells
• Large skillet – for cooking the ground beef and spinach
• Mixing bowl – to combine the cheese filling
• Baking dish (approximately 9×13 inches) – perfect size for layering and baking
• Spoon or spatula – for stirring and assembling
• Piping bag or resealable plastic bag (optional) – makes filling the shells easier and less messy

Make Beef and Spinach Stuffed Manicotti: A Simple Method

Step 1: Prepare the Manicotti Shells

Bring a large pot of salted water to a boil. Add the manicotti shells and cook until just al dente, about 7 to 8 minutes. Drain carefully and rinse under cold water to stop cooking. Lay the shells flat on a lightly oiled baking sheet to prevent sticking while you prepare the filling.

Step 2: Cook the Ground Beef and Spinach

Heat a drizzle of olive oil in a large skillet over medium heat. Add the minced garlic and sauté for about 1 minute until fragrant. Add the ground beef, breaking it up with a spoon, and cook until browned and no longer pink, about 6 to 8 minutes. Season with salt, pepper, and Italian seasoning. Stir in the chopped spinach and cook just until wilted, about 2 minutes. Remove from heat and let cool slightly.

Step 3: Combine the Filling

In a mixing bowl, combine the ricotta cheese, half of the shredded mozzarella, grated Parmesan, and the cooked beef and spinach mixture. Stir until everything is evenly incorporated. Adjust seasoning if needed.

Step 4: Stuff the Manicotti Shells

Using a spoon or a piping bag, fill each manicotti shell generously with the beef and spinach mixture. Take your time to ensure each shell is nicely packed without breaking.

Step 5: Assemble and Bake

Preheat your oven to 350°F (175°C). Spread about 1 cup of marinara sauce evenly over the bottom of your baking dish. Arrange the stuffed shells in a single layer on top of the sauce. Pour the remaining marinara sauce over the shells and sprinkle the top with the remaining mozzarella cheese.

Step 6: Bake to Perfection

Cover the baking dish with foil and bake for 25 minutes. Remove the foil and bake for an additional 10 minutes or until the cheese is melted and bubbly. Let the manicotti rest for a few minutes before serving.

In-Season Swaps

• Replace fresh spinach with kale or Swiss chard for a heartier green.
• Swap ground beef with ground turkey or lamb to vary the protein.
• Use a homemade tomato sauce infused with fresh basil and oregano for extra freshness.
• Add sautéed mushrooms or diced bell peppers to the filling for more texture.

What I Learned Testing

While perfecting this Beef and Spinach Stuffed Manicotti, I discovered a few tips that make all the difference:

• Cooking the manicotti shells just until al dente helps prevent tearing during stuffing.
• Cooling the beef and spinach mixture before combining with cheese ensures the filling doesn’t become watery.
• Using a piping bag to fill the shells saves time and keeps things neat.
• Letting the baked dish rest before serving helps the sauce thicken and the flavors meld beautifully.

Make-Ahead & Storage

This dish is ideal for meal prep and leftovers. You can assemble the stuffed manicotti in advance and refrigerate it covered for up to 24 hours before baking. After baking, leftovers store well in an airtight container in the fridge for 3 to 4 days. Reheat in the oven at 350°F (175°C) until warmed through to preserve texture and flavor. You can also freeze the unbaked assembled dish for up to 2 months—just thaw overnight in the refrigerator before baking.

Troubleshooting Q&A

How do I prevent the manicotti shells from breaking when stuffing?

Cook the shells just until al dente and rinse with cold water immediately. Handle them gently and use a piping bag for easier filling. If a shell tears, simply patch it with a bit of the filling or set it aside for a different use.

Can I make this recipe vegetarian?

Absolutely! Substitute the ground beef with sautéed mushrooms, lentils, or a plant-based meat alternative. Increase the seasoning to boost flavor and keep the spinach and cheeses for richness.

What kind of marinara sauce works best?

A classic, well-seasoned marinara sauce with garlic, herbs, and ripe tomatoes pairs perfectly. You can use store-bought or homemade. For a more vibrant flavor, try adding fresh basil or a splash of red wine to your sauce.

Why is my filling watery?

Make sure to squeeze excess moisture out of the spinach before mixing it in. Also, allow the cooked beef and spinach mixture to cool before combining with the cheeses to prevent the filling from becoming too runny.

More from the Kitchen

• Apple Walnut Spinach Salad – a fresh and crunchy side that pairs beautifully with baked pasta dishes.
• The Best Homemade Lasagna Recipe – another cozy Italian classic to enjoy on a chilly night.
• Baked Ziti Recipe – a cheesy, comforting pasta bake that’s easy and crowd-pleasing.

See You at the Table

This Beef and Spinach Stuffed Manicotti is more than just a meal—it’s a celebration of flavors and textures that come together effortlessly to impress. Whether it’s a weeknight dinner or a weekend feast, this dish offers a satisfying and wholesome way to enjoy pasta filled with hearty beef and vibrant greens. Pair it with a crisp green salad or garlic bread, and you have a meal everyone will love. So grab your apron, get cooking, and savor every delicious bite!

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