Cheesy Ground Turkey Pasta Casserole

If you’re on the hunt for a comforting, hearty meal that combines the best of cheesy goodness with lean protein and pasta, this Cheesy Ground Turkey Pasta Casserole is about to become your new favorite. It’s a one-dish wonder that brings together juicy ground turkey, perfectly cooked pasta, and a luscious blend of mozzarella and cheddar cheeses, all simmered in a rich tomato sauce seasoned with Italian herbs. Whether you’re feeding a family, prepping for the week ahead, or just craving something cozy, this casserole hits all the right notes.

Why Cheesy Ground Turkey Pasta Casserole is Worth Your Time

There’s something incredibly satisfying about a baked pasta casserole loaded with cheese and flavorful ingredients. This dish is not just delicious; it’s also a balanced meal packed with protein, carbs, and a hit of veggies from the tomatoes and onions. Using ground turkey keeps it lighter than traditional beef casseroles without sacrificing any of the rich taste or texture. Plus, it’s super versatile and customizable, making it perfect for busy weeknights or casual gatherings. The melty cheese topping creates a golden, bubbly crust that’s utterly irresistible.

This recipe is straightforward to make, uses pantry staples, and delivers a comforting dish that everyone will love. It’s one of those meals that feels like a warm hug on a plate—rich, cheesy, and wholesome.

The Essentials

• 1 pound ground turkey: Provides lean protein and a mild flavor that absorbs the seasoning beautifully.
• 12 ounces pasta: Elbow or penne pasta works best, holding onto the sauce and cheese perfectly.
• 1 can (15 ounces) diced tomatoes, undrained: Adds moisture and a fresh tomato flavor.
• 1 can (15 ounces) tomato sauce: Creates a rich, saucy base for the casserole.
• 1 cup shredded mozzarella cheese: Melts smoothly for that classic cheesy stretch.
• 1 cup shredded cheddar cheese: Adds sharpness and depth to the cheese blend.
• 1 medium onion, diced: Builds savory flavor and texture.
• 2 cloves garlic, minced: Infuses the dish with aromatic warmth.
• 1 teaspoon Italian seasoning: A blend of herbs that brings a Mediterranean flair.
• Salt and pepper to taste: Essential for balancing and enhancing flavors.
• 2 tablespoons olive oil: For sautéing the aromatics and turkey.
• Fresh parsley for garnish (optional): Adds a pop of color and fresh flavor.

Tools of the Trade

• Large pot: For boiling pasta to perfect tenderness.
• Large skillet: To brown the ground turkey and sauté onions and garlic.
• Mixing spoon: To combine ingredients evenly.
• 9×13-inch baking dish: Ideal size for layering and baking the casserole.
• Measuring cups and spoons: To ensure precise ingredient amounts.
• Cheese grater: For freshly shredding mozzarella and cheddar (optional but recommended).

Cheesy Ground Turkey Pasta Casserole: Step-by-Step Guide

Step 1: Prepare the Pasta

Start by bringing a large pot of salted water to a boil. Add 12 ounces of pasta (elbow or penne) and cook according to the package instructions until al dente. Drain the pasta and set it aside while you prepare the sauce.

Step 2: Cook the Ground Turkey

Heat 2 tablespoons of olive oil in a large skillet over medium heat. Add the diced onion and sauté for about 3-4 minutes until translucent. Toss in the minced garlic and cook for another 30 seconds until fragrant.

Add the ground turkey to the skillet, breaking it apart with a spoon. Cook until the turkey is no longer pink and starts to brown, about 6-8 minutes. Season with salt, pepper, and 1 teaspoon Italian seasoning while it cooks.

Step 3: Add Tomatoes and Sauce

Pour in the can of diced tomatoes (with juices) and the tomato sauce. Stir everything together, letting the mixture simmer for 5-7 minutes to blend the flavors and thicken slightly.

Step 4: Combine Pasta and Sauce

In a large mixing bowl or directly in the skillet (if large enough), combine the cooked pasta with the turkey tomato sauce mixture. Stir in half of the shredded mozzarella and cheddar cheese, mixing until evenly distributed.

Step 5: Assemble the Casserole

Preheat your oven to 375°F (190°C). Transfer the pasta mixture into a greased 9×13-inch baking dish, spreading it out evenly. Sprinkle the remaining mozzarella and cheddar cheese on top for a golden, cheesy crust.

Step 6: Bake Until Bubbly and Golden

Bake the casserole in the preheated oven for 20-25 minutes, or until the cheese is melted, bubbly, and lightly browned on top. If you want an extra crispy top, you can broil it for an additional 2-3 minutes—just watch it closely to prevent burning.

Step 7: Garnish and Serve

Remove from the oven and let the casserole cool for a few minutes. Garnish with freshly chopped parsley if desired, then serve warm and enjoy!

Ingredient Swaps & Substitutions

• Ground turkey: You can use ground chicken or lean ground beef for different flavor profiles.
• Pasta: Swap elbow or penne with rotini, rigatoni, or even gluten-free pasta.
• Cheese: Try swapping cheddar with pepper jack for a spicy kick or gouda for a smoky flavor.
• Tomatoes: Use fresh diced tomatoes if you prefer, just reduce the added liquid slightly.
• Italian seasoning: Fresh herbs like basil, oregano, or thyme can be used instead if you have them on hand.
• Onion and garlic: Shallots or green onions make a great alternative for a milder taste.

Little Things that Matter

• Don’t overcook the pasta initially; it will cook more in the oven and absorb flavors from the sauce.

• Use freshly shredded cheese instead of pre-shredded for better melt and creaminess.

• Let the casserole rest for a few minutes after baking to set up and make serving easier.

• For added texture, stir in some sautéed mushrooms or bell peppers with the onions.

• A splash of red pepper flakes into the sauce can add a subtle heat if you like a little spice.

Store, Freeze & Reheat

This Cheesy Ground Turkey Pasta Casserole is a fantastic make-ahead meal. Store leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, microwave individual portions or warm in the oven at 350°F (175°C) until heated through.

For freezing, let the casserole cool completely, then cover tightly with foil and plastic wrap before freezing. It will keep well for up to 3 months. Thaw overnight in the refrigerator and bake at 350°F until warmed through and bubbly.

Ask & Learn

Can I make this casserole ahead of time?

Absolutely! You can assemble the casserole a day in advance, cover it with foil, and refrigerate. When ready, just bake it as directed, adding a few extra minutes if it’s coming straight from the fridge.

Is it okay to use frozen ground turkey?

Yes, just be sure to thaw it completely before cooking. Cooking frozen turkey directly can result in uneven cooking and affect the texture.

How can I make this recipe dairy-free?

Swap the mozzarella and cheddar cheese with your favorite dairy-free cheese alternatives. Nutritional yeast can also add a cheesy flavor boost if you want to skip cheese altogether.

What sides pair well with this casserole?

A crisp green salad or steamed veggies like broccoli or green beans complement the richness of this dish perfectly. Garlic bread or a simple baguette also makes a great accompaniment.

Don’t Miss These

• Cheesy Bbq Chicken Pasta Casserole – Another crowd-pleaser with a smoky BBQ twist.
• Mac And Cheese Style Pasta Bake – A creamy and indulgent take on classic mac and cheese.
• Baked Four Cheese Ziti – Perfect for cheese lovers looking for a rich, layered pasta bake.

Time to Try It

Now that you have all the tips, tricks, and know-how to make this Cheesy Ground Turkey Pasta Casserole, it’s time to roll up your sleeves and get cooking. This recipe is a fantastic way to enjoy a wholesome, cheesy meal that’s as satisfying as it is easy to prepare. Whether you’re cooking for your family or meal prepping for the week, this casserole delivers comfort and flavor in every bite. Enjoy the melty cheese, hearty turkey, and saucy pasta — a combination that’s truly unbeatable!

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