Creamy Lemon Chicken Penne Bake

If you’re on the lookout for a comforting, luscious pasta dish that’s bursting with fresh lemon flavor and tender chicken, this Creamy Lemon Chicken Penne Bake is your new best friend. It’s perfectly balanced—creamy yet bright, hearty yet fresh. The baked penne pasta coated in a rich, garlicky lemon cream sauce with juicy chicken and spinach makes it a one-dish meal that satisfies every craving. And the golden breadcrumb topping adds just the right crunch to complete this irresistible dinner.

Why It’s My Go-To

There’s something magical about the way lemon elevates a creamy dish without overpowering it, and this recipe nails that balance beautifully every single time. It’s quick enough for weeknights but special enough to serve guests, making it a versatile staple in my kitchen. Plus, the combination of tender chicken, Parmesan, and fresh spinach creates a harmony of flavors and textures that keeps me coming back for more. I also love how adaptable this dish is—you can tweak the herbs or add veggies to suit your mood or what’s in your pantry. This Creamy Lemon Chicken Penne Bake is my ultimate cozy, crowd-pleasing meal.

What You’ll Gather

• 12 ounces penne pasta – perfectly shaped to hold the creamy sauce
• 1 lb chicken breast, diced – tender and juicy protein
• 1 tablespoon olive oil – for sautéing
• 3 cloves garlic, minced – aromatic flavor base
• 1 cup heavy cream – rich and velvety sauce
• 1 cup chicken broth – adds depth and moisture
• 1 cup grated Parmesan cheese – salty, nutty goodness
• 1 lemon, zested and juiced – bright citrus punch
• 1 teaspoon dried thyme – earthy herbal note
• Salt and pepper, to taste
• 1 cup fresh spinach – adds color and nutrition
• 1/2 cup breadcrumbs – crunchy topping
• 1 tablespoon parsley, chopped – fresh garnish

Setup & Equipment

• Large pot – for boiling the penne pasta
• Large skillet – to cook the chicken and prepare the sauce
• Baking dish (about 9×13 inches) – for assembling and baking the pasta
• Mixing spoon and spatula – to stir the sauce and pasta
• Grater – for fresh Parmesan and lemon zest
• Knife and cutting board – to dice chicken and chop parsley

Directions: Creamy Lemon Chicken Penne Bake

Step 1: Cook the Penne

Bring a large pot of salted water to a boil. Add the penne pasta and cook according to package instructions until al dente, usually around 9-11 minutes. Drain and set aside.

Step 2: Sauté the Chicken

Heat olive oil in a large skillet over medium heat. Add the diced chicken breast and season with salt, pepper, and dried thyme. Cook until golden and cooked through, about 5-7 minutes. Remove the chicken from the skillet and set aside.

Step 3: Build the Creamy Lemon Sauce

In the same skillet, add the minced garlic and sauté for about 1 minute until fragrant. Pour in the chicken broth, heavy cream, lemon zest, and lemon juice. Stir well and bring the mixture to a gentle simmer. Let it cook for 3-4 minutes to thicken slightly.

Step 4: Combine the Ingredients

Reduce heat to low. Stir in the grated Parmesan cheese until melted and the sauce is creamy and smooth. Add the cooked penne, sautéed chicken, and fresh spinach to the skillet. Toss everything together to coat evenly and wilt the spinach.

Step 5: Assemble & Bake

Preheat your oven to 375°F (190°C). Transfer the creamy mixture into a greased baking dish. Sprinkle the breadcrumbs evenly over the top for a crispy golden crust.

Step 6: Bake & Garnish

Bake uncovered for 20-25 minutes until the top is golden and bubbly. Remove from the oven and sprinkle with chopped parsley before serving.

Seasonal Twists

• Swap spinach for kale or swiss chard for a heartier green
• Add roasted cherry tomatoes for a sweet, roasted burst
• Incorporate sun dried tomatoes for an intense, tangy flavor (similar to my Creamy Sun Dried Tomato Chicken Pasta)
• Mix in sautéed mushrooms or asparagus tips to add earthiness and texture

Testing Timeline

• Cooked penne just shy of al dente for the best texture after baking
• Used fresh lemon zest and juice to brighten the creamy sauce without overpowering
• Tested baking time to achieve a golden crust without drying the pasta
• Adjusted seasoning throughout to balance richness and acidity

Storage & Reheat Guide

Once cooled, store leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place the bake in an oven-safe dish, cover loosely with foil, and warm at 350°F (175°C) for 15-20 minutes or until heated through. Alternatively, microwave individual portions covered with a damp paper towel for 2-3 minutes, stirring halfway.

Frequently Asked Questions

Can I use other types of pasta besides penne?

Absolutely! Rigatoni, ziti, or even fusilli work well because they hold the sauce nicely. Just adjust cooking times as needed.

Is this recipe freezer-friendly?

Yes, you can freeze the assembled bake before baking. Wrap tightly and freeze for up to 2 months. Thaw overnight in the fridge before baking.

Can I make this dairy-free?

To make a dairy-free version, substitute heavy cream with coconut cream or a plant-based alternative, and use a dairy-free Parmesan substitute.

How can I add more veggies to this dish?

Feel free to toss in extra vegetables like bell peppers, zucchini, or peas when combining the sauce and pasta to boost nutrition and flavor.

Serve with These

• Chicken Bacon Alfredo Baked Pasta – if you want a creamier, indulgent pasta option for variety
• Creamy Sun Dried Tomato Chicken Pasta – for a tangy, tomato-rich companion dish
• Garlic bread or crusty baguette – perfect for soaking up any extra sauce
• Simple green salad with vinaigrette – for a fresh contrast

Hungry for More?

If this Creamy Lemon Chicken Penne Bake has you craving more comforting pasta dinners, be sure to check out other easy-bake recipes that combine rich, cheesy sauces with tender chicken and bright flavors. From classic baked pastas to unique twists like incorporating bacon or sun dried tomatoes, there’s always a way to elevate your weeknight meals.

Creamy Lemon Chicken Penne Bake is one of those dishes that feels like a warm hug on a plate—perfect for when you want something both nourishing and indulgent. Its bright lemon essence cuts through the creaminess, making it a refreshing take on traditional baked pasta casseroles. Whether you’re cooking for family or meal prepping for the week, this recipe will quickly become a favorite in your rotation. So grab your ingredients, and get ready to enjoy a dish that’s as comforting as it is delicious!

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