One-Pan Cajun Chicken Pasta Bake

If you’re searching for a dish that brings bold flavors, ease, and comfort all in one pan, this One-Pan Cajun Chicken Pasta Bake is your new go-to. It’s a perfect weeknight dinner that packs a punch with its Cajun seasoning and creamy sauce, balanced by tender chicken and hearty pasta. Imagine a dish where tender chicken pieces, vibrant bell peppers, and aromatic spices mingle with penne pasta in a luscious, cheesy sauce—all cooked effortlessly in a single pan. It’s a flavor-packed meal that’s as satisfying as it is simple to make.

Why You’ll Keep Making It

This One-Pan Cajun Chicken Pasta Bake quickly becomes a favorite because it balances bold Cajun spices with creamy, cheesy goodness. The convenience of cooking everything in one pan means less cleanup and more time to enjoy your meal. It’s versatile too—perfect for family dinners, meal prep, or impressing guests without spending hours in the kitchen. Plus, the dish is customizable with your favorite vegetables or cheeses, making it a flexible recipe to refine and enjoy again and again.

What You’ll Need

• 2 tablespoons olive oil
• 1 pound chicken breast, cut into bite-sized pieces
• 1 tablespoon Cajun seasoning
• 1 bell pepper, diced
• 1 onion, diced
• 3 cloves garlic, minced
• 8 ounces penne pasta
• 4 cups chicken broth
• 1 can diced tomatoes (14.5 oz), undrained
• 1 cup heavy cream
• 1 cup shredded cheddar cheese
• Salt and pepper to taste
• Fresh parsley, chopped (for garnish)

Recommended Tools

• Large deep skillet or sauté pan: Essential for cooking chicken and pasta together without spills.
• Sharp chef’s knife: For dicing vegetables and cutting chicken into bite-sized pieces.
• Wooden spoon or silicone spatula: To stir everything evenly and prevent sticking.
• Measuring cups and spoons: To get your ingredients just right.

Step-by-Step: One-Pan Cajun Chicken Pasta Bake

Step 1: Sauté the Chicken

Heat 2 tablespoons of olive oil in your large skillet over medium-high heat. Toss the bite-sized chicken pieces with 1 tablespoon of Cajun seasoning, ensuring each piece is well-coated. Add the chicken to the hot pan and cook until browned on all sides and cooked through, about 5-7 minutes. Remove the chicken from the pan and set aside.

Step 2: Cook the Vegetables

In the same skillet, add diced onion and bell pepper. Sauté for 3-4 minutes until softened and fragrant. Add minced garlic and cook for an additional minute, stirring constantly to avoid burning.

Step 3: Combine Pasta and Liquids

Add the uncooked penne pasta to the skillet, followed by the chicken broth and the entire can of diced tomatoes with their juice. Stir to combine and bring the mixture to a simmer.

Step 4: Simmer and Cook Pasta

Cover the skillet, reduce the heat to medium-low, and let the pasta cook for about 12 minutes, or until the pasta is tender and most of the liquid has been absorbed. Stir occasionally to prevent sticking.

Step 5: Add Cream and Cheese

Return the cooked chicken to the skillet. Pour in 1 cup of heavy cream, stirring to combine. Sprinkle the shredded cheddar cheese over the top, then cover the pan again and cook for 3-5 minutes until the cheese melts into a creamy sauce.

Step 6: Season and Garnish

Taste and season with salt and pepper as needed. Sprinkle fresh parsley over the top for a burst of color and freshness. Serve hot and enjoy your perfectly creamy, spicy, and comforting One-Pan Cajun Chicken Pasta Bake.

Healthier Substitutions

• Use olive oil spray or reduce olive oil to 1 tablespoon to cut calories.
• Swap heavy cream with coconut milk or a lower-fat cream alternative for a lighter sauce.
• Use whole wheat or gluten-free penne pasta to boost fiber or accommodate dietary needs.
• Replace cheddar cheese with a reduced-fat cheese or nutritional yeast for a dairy-free option.
• Add extra veggies like zucchini or spinach for added nutrients and volume.

Pitfalls & How to Prevent Them

Overcooking the pasta can make the dish mushy, so keep a close eye on the simmering time and test the pasta often. If the liquid evaporates too quickly before the pasta is tender, add a splash more chicken broth or water to prevent sticking. Be mindful not to burn the garlic during the sauté stage—add it after the onions and peppers have softened. Lastly, stirring occasionally while simmering helps even cooking and prevents pasta from sticking to the pan.

Prep Ahead & Store

You can prepare this One-Pan Cajun Chicken Pasta Bake up to a day in advance. Simply cook the dish as instructed, then allow it to cool completely before transferring it to an airtight container. Store in the refrigerator for up to 3 days. To reheat, warm on the stove over low heat or in the microwave, adding a splash of chicken broth or cream to loosen the sauce if needed. This dish also freezes well—freeze in portions for up to 2 months, then thaw overnight in the fridge before reheating.

Your Questions, Answered

Can I use a different type of pasta?

Absolutely! While penne is ideal for holding the sauce and mixing well with the ingredients, you can substitute with rigatoni, rotini, or even shells. Just adjust the cooking time as needed depending on the pasta shape.

Is this recipe very spicy?

The Cajun seasoning adds a nice kick, but the cream and cheese balance the heat. If you prefer milder flavors, reduce the Cajun seasoning to 1 teaspoon or use a mild seasoning blend. For an extra spicy twist, feel free to add crushed red pepper flakes.

Can I make this dish vegetarian?

Definitely! Replace the chicken with hearty vegetables like mushrooms or eggplant, or use a plant-based protein substitute. For a similar comfort vibe, try our Creamy Mushroom Chicken Pasta Casserole for inspiration on creamy, veggie-packed pasta dishes.

What can I serve with this pasta bake?

This One-Pan Cajun Chicken Pasta Bake is a complete meal on its own, but a simple side salad or steamed green beans would complement it nicely. For more Cajun-inspired pasta options, you might enjoy the Spicy Cajun Andouille Sausage Pasta or the rich and flavorful Creamy Cajun Shrimp Pasta.

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Bring It to the Table

This One-Pan Cajun Chicken Pasta Bake is a crowd-pleaser that looks as inviting as it tastes. Bring it straight from the skillet to your dinner table for a warm, comforting meal with minimal fuss. Garnished with fresh parsley, it adds a pop of color and freshness to each serving. Pair it with a crisp side salad or crusty bread to soak up every bit of that creamy, spicy sauce. Whether it’s a busy weeknight or a casual weekend dinner, this pasta bake will have everyone asking for seconds.

With its rich flavors, ease of preparation, and minimal cleanup, the One-Pan Cajun Chicken Pasta Bake is destined to become a staple in your recipe collection. Enjoy the perfect blend of spice, creaminess, and cheesy indulgence that makes every bite memorable.

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