Cheesy Chicken Fajita Pasta Casserole

If you’re craving a comforting, cheesy, and flavor-packed dinner that’s perfect for weeknights, look no further than this Cheesy Chicken Fajita Pasta Casserole. This dish combines tender chunks of chicken breast with sautéed bell peppers and onions, all seasoned with a blend of chili powder, cumin, paprika, and oregano. The pasta is cooked to al dente perfection, then tossed in a creamy sauce made of chicken broth and sour cream, topped with melty cheddar and mozzarella cheeses. The result? A vibrant, satisfying casserole bursting with Tex-Mex vibes that the whole family will love.

Why I Love This Recipe

This Cheesy Chicken Fajita Pasta Casserole is a total winner in my book for so many reasons. First, it’s incredibly easy to throw together, especially on busy nights when you want a hearty meal without fuss. The combination of classic fajita spices with pasta is a fun twist that feels both familiar and fresh. I love how the sour cream adds a creamy tang that balances the spices perfectly, while the double cheese topping creates that irresistible golden crust. Plus, it’s a one-dish meal that pairs protein, veggies, and carbs all in one pan, saving me cleanup time.

Whether you’re cooking for picky eaters, meal prepping for the week, or hosting a casual dinner, this casserole hits all the right notes. And if you’re a fan of dishes like Loaded Taco Pasta Bake or want to try something equally delicious, this recipe will surely become a new favorite.

Shopping List

• 8 oz penne pasta
• 1 lb chicken breast, diced
• 1 tablespoon olive oil
• 1 bell pepper, sliced (any color you prefer)
• 1 onion, chopped
• 2 cloves garlic, minced
• 1 teaspoon chili powder
• 1 teaspoon cumin
• 1/2 teaspoon paprika
• 1/2 teaspoon oregano
• 1/2 teaspoon salt
• 1/4 teaspoon black pepper
• 1 cup chicken broth
• 1 cup sour cream
• 1 cup shredded cheddar cheese
• 1 cup shredded mozzarella cheese
• 1/4 cup chopped fresh cilantro (optional)

Equipment & Tools

• Large pot – for boiling the penne pasta
• Large skillet or sauté pan – to cook the chicken and veggies
• Mixing bowl – to combine the sauce ingredients
• Baking dish (about 9×13 inches) – for assembling and baking the casserole
• Wooden spoon or spatula – for stirring and mixing
• Measuring cups and spoons – to ensure accurate seasoning and ingredient amounts

Cooking Cheesy Chicken Fajita Pasta Casserole: The Process

Step 1: Cook the Penne Pasta

Bring a large pot of salted water to a boil. Add the 8 oz of penne pasta and cook according to package instructions until al dente, usually about 9-11 minutes. Drain the pasta well and set it aside.

Step 2: Sauté the Chicken

In a large skillet, heat 1 tablespoon of olive oil over medium-high heat. Add the diced chicken breast and cook, stirring occasionally, until the chicken is no longer pink and cooked through, about 6-8 minutes. Remove the chicken from the skillet and set aside.

Step 3: Cook the Vegetables

In the same skillet, add the chopped onion and sliced bell pepper. Sauté for about 5 minutes until the veggies are tender and slightly caramelized. Add the minced garlic and cook for another 1-2 minutes until fragrant.

Step 4: Add Spices

Sprinkle in 1 teaspoon chili powder, 1 teaspoon cumin, 1/2 teaspoon paprika, 1/2 teaspoon oregano, 1/2 teaspoon salt, and 1/4 teaspoon black pepper. Stir well to coat the vegetables and garlic evenly with the spices.

Step 5: Combine Chicken and Broth

Return the cooked chicken to the skillet. Pour in 1 cup of chicken broth and stir everything together. Let the mixture simmer for 3-4 minutes to blend the flavors and slightly reduce the broth.

Step 6: Mix in Sour Cream and Pasta

Remove the skillet from heat and stir in 1 cup of sour cream until smooth and creamy. Then fold in the cooked penne pasta, making sure every piece is coated in the luscious sauce.

Step 7: Assemble the Casserole

Transfer the entire mixture into a greased 9×13-inch baking dish. Sprinkle 1 cup of shredded cheddar cheese and 1 cup of shredded mozzarella cheese evenly over the top.

Step 8: Bake

Preheat your oven to 375°F (190°C). Bake the casserole for 20-25 minutes, or until the cheese is melted, bubbly, and lightly golden on top.

Step 9: Garnish and Serve

Once out of the oven, sprinkle 1/4 cup of chopped fresh cilantro over the casserole if you like a fresh herbal note. Serve hot and enjoy the cheesy, spicy goodness!

If You’re Out Of…

• Chicken breast: You can substitute with diced turkey breast or even firm tofu for a vegetarian twist.
• Penne pasta: Rotini, rigatoni, or even elbow macaroni work well as substitutes.
• Chicken broth: Use vegetable broth or water with a pinch of bouillon cube for extra flavor.
• Sour cream: Greek yogurt is a great alternative that adds tang and creaminess.
• Cheddar or mozzarella cheese: Try pepper jack or Monterey Jack for a different cheese flavor.
• Fresh cilantro: Parsley or green onions can be used as a fresh garnish instead.

Don’t Do This

• Don’t overcook the pasta in the boiling water; it should be al dente since it will cook more in the oven.
• Don’t skip sautéing the vegetables — it adds depth to the flavors and softens the peppers and onions.
• Don’t forget to season the chicken and vegetables well with spices; bland protein will make the dish less exciting.
• Don’t overload the casserole with too much cheese — balance is key to a creamy but not greasy texture.

Meal Prep & Storage Notes

This Cheesy Chicken Fajita Pasta Casserole is fantastic for meal prep. You can assemble it ahead of time and store it covered in the refrigerator for up to 2 days before baking. If you want to save time on a busy night, prepare everything through Step 7, then cover and refrigerate. When ready to eat, bake as directed, adding a few extra minutes if baking cold.

Leftovers keep well in an airtight container in the fridge for up to 3 days. Reheat gently in the microwave or oven until warmed through. You can also freeze portions for up to 2 months; thaw overnight in the fridge before reheating.

FAQ

Can I use frozen chicken instead of fresh?

Yes, you can use frozen diced chicken breast. Just make sure to thaw it completely in the refrigerator before cooking to ensure even cooking and food safety.

Can I make this recipe spicy?

Absolutely! Add extra chili powder, a pinch of cayenne pepper, or some diced jalapeños when cooking the vegetables to kick up the heat.

Is this recipe suitable for meal prepping?

Definitely. This casserole holds up well in the fridge and can be baked fresh when you’re ready, making it a convenient meal prep option.

Can I add other vegetables to this casserole?

Yes! Feel free to add sliced mushrooms, corn, or zucchini along with the bell peppers for added nutrition and flavor.

What to Make After This

• Try the creamy and comforting Tuscan Garlic Chicken Pasta for your next dinner.
• For another cheesy pasta bake with a Mexican twist, check out the Loaded Taco Pasta Bake.
• Whip up a fresh side salad with lime vinaigrette to complement any Tex-Mex inspired meal.
• Make a batch of homemade guacamole to serve alongside your casserole for extra creaminess and flavor.

Bring It to the Table

This Cheesy Chicken Fajita Pasta Casserole is best served hot and fresh from the oven, with melted cheese stretching delightfully with every forkful. Garnish with a sprinkle of fresh cilantro to add a pop of color and freshness. Pair it with a crisp green salad or some warm tortilla chips and salsa for a complete meal. It’s a crowd-pleaser that’s perfect for family dinners, potlucks, or anytime you want a delicious, satisfying dish with a hint of spice and a whole lot of cheesy goodness. Enjoy!

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