Chicken Alfredo Lasagna Rollup Bake

If you’re craving a dish that’s creamy, comforting, and packed with cheesy goodness, look no further than this Chicken Alfredo Lasagna Rollup Bake. It’s a delightful twist on classic lasagna, where traditional layers are replaced with rolled-up noodles stuffed with a luscious mixture of shredded chicken, ricotta, and Parmesan cheeses, all smothered in rich Alfredo sauce. This dish brings together the best parts of Italian comfort food with an easy-to-assemble format that’s perfect for busy weeknights or a weekend dinner with family and friends.

Why You’ll Keep Making It

This Chicken Alfredo Lasagna Rollup Bake is a total crowd-pleaser that combines convenience and flavor. Unlike a traditional lasagna that requires layering multiple pans and more time, rollups are quick to assemble and bake evenly. The creamy Alfredo sauce complements the tender chicken and cheeses perfectly, creating a luscious dish that feels indulgent without being complicated. Plus, it reheats beautifully, making it great for leftovers or meal prep. Whether you’re a seasoned cook or just starting out, this recipe is straightforward, forgiving, and sure to become a staple in your dinner rotation.

What Goes Into Chicken Alfredo Lasagna Rollup Bake

• 9 lasagna noodles: Cooked according to package instructions until al dente.
• 2 cups cooked chicken, shredded: Use rotisserie chicken or poached chicken breasts for ease.
• 2 cups ricotta cheese: Creamy and mild, it creates a smooth filling base.
• 1 cup grated Parmesan cheese: Adds a sharp, nutty flavor that enhances the filling.
• 2 cups shredded mozzarella cheese: Melts beautifully for that gooey, cheesy texture.
• 2 cups Alfredo sauce: Rich and creamy, it ties all the flavors together.
• 1 teaspoon garlic powder: Provides subtle depth without overpowering.
• 1 teaspoon Italian seasoning: A blend of herbs that brings classic Italian flair.
• Salt and pepper to taste: To balance and enhance all the flavors.
• Fresh parsley for garnish: Adds a pop of color and fresh herbal note.

Equipment Breakdown

• Large pot: For boiling the lasagna noodles.
• Colander: To drain the cooked noodles.
• Mixing bowl: To combine the chicken, cheeses, and seasonings.
• 9×13-inch baking dish: Perfect size to arrange and bake the rollups.
• Spoon or spatula: To spread the filling evenly on the noodles.
• Aluminum foil: To cover the dish during baking and keep it moist.

The Method for Chicken Alfredo Lasagna Rollup Bake

Step 1: Cook the noodles

Bring a large pot of salted water to a boil. Cook the 9 lasagna noodles according to the package instructions until just al dente. Drain and lay them flat on a lightly oiled baking sheet or parchment paper to prevent sticking.

Step 2: Prepare the filling

In a large mixing bowl, combine the shredded chicken, ricotta cheese, grated Parmesan, garlic powder, Italian seasoning, salt, and pepper. Mix well until all ingredients are evenly incorporated.

Step 3: Assemble the rollups

Take one noodle at a time and spread approximately ¼ cup of the filling mixture evenly over the entire surface. Carefully roll the noodle from one end to the other, creating a tight roll. Place each roll seam-side down in the prepared baking dish.

Step 4: Add sauce and cheese

Pour the Alfredo sauce evenly over the lasagna rollups. Sprinkle the shredded mozzarella cheese on top, ensuring each roll is nicely covered to get that golden, bubbly crust.

Step 5: Bake

Cover the dish loosely with aluminum foil and bake in a preheated oven at 375°F (190°C) for about 25 minutes. Then remove the foil and bake for an additional 10 minutes or until the cheese is melted and slightly golden.

Step 6: Garnish and serve

Once out of the oven, let the dish rest for 5 minutes. Sprinkle freshly chopped parsley on top for a burst of color and fresh flavor. Serve warm and enjoy!

Tailor It to Your Diet

• Make it vegetarian: Substitute the chicken with sautéed mushrooms or roasted vegetables.
• Lower fat: Use part-skim ricotta and mozzarella cheeses, and a light Alfredo sauce option.
• Gluten-free: Swap regular lasagna noodles with gluten-free lasagna noodles.
• Dairy-free: Try dairy-free ricotta and mozzarella alternatives and a creamy coconut-based Alfredo sauce.

Flavor Logic

The richness of the Alfredo sauce melds perfectly with the tender chicken and creamy cheeses, creating a harmonious balance of flavors and textures. Garlic powder and Italian seasoning infuse the filling with subtle aromatic notes, while Parmesan adds a sharp umami kick. The mozzarella on top melts to golden perfection, providing that irresistible gooey layer we all crave in baked pasta dishes. Fresh parsley is not just for looks—it brightens the palate and adds a fresh, herbal finish that cuts through the richness.

How to Store & Reheat

Store any leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, place individual servings on a microwave-safe plate and warm in 30-second intervals until heated through. Alternatively, you can reheat the entire dish in a 350°F (175°C) oven covered with foil for 15-20 minutes, until warmed throughout. This method helps maintain the creamy texture and keeps the cheese from drying out.

Handy Q&A

Can I use pre-cooked rotisserie chicken for this recipe?

Absolutely! Using rotisserie chicken is a fantastic time-saver and adds great flavor to your Chicken Alfredo Lasagna Rollup Bake. Just shred it and mix with the ricotta and seasonings.

Can I make the rollups ahead of time?

Yes, you can assemble the rollups a day in advance. Cover them tightly with plastic wrap and refrigerate. When ready to bake, simply add the Alfredo sauce and cheese, then bake as directed.

What if I don’t have Alfredo sauce on hand?

You can make a quick Alfredo sauce by melting butter in a saucepan, adding minced garlic, then stirring in heavy cream and grated Parmesan until thickened. There are also great store-bought options available if you’re short on time.

Can I freeze the Chicken Alfredo Lasagna Rollup Bake?

Yes! Freeze the unbaked rollups in a single layer on a baking sheet, then transfer to a freezer-safe container. Bake from frozen, just increase the baking time by about 15-20 minutes and cover with foil to prevent over-browning.

Our Most-Loved Recipes

• Baked Chicken Ziti Alfredo – Another creamy pasta bake with tender chicken and cheesy goodness.
• Cheesy Alfredo Chicken Pasta Casserole – A quick and easy casserole packed with Alfredo sauce and chicken.

Final Thoughts

This Chicken Alfredo Lasagna Rollup Bake is a perfect combination of ease and indulgence. The use of rolled noodles keeps the assembly simple and neat, while the creamy filling and Alfredo sauce evoke that classic Italian comfort food vibe. It’s a dish that’s sure to impress at the dinner table, whether you’re feeding a family or entertaining guests. The recipe’s versatility also means you can easily tweak it to suit your preferences or dietary needs without sacrificing flavor. If you love rich, cheesy pasta dishes, this bake will quickly become a go-to recipe in your kitchen.

With its luscious layers, creamy texture, and satisfying flavors, this dish is an excellent way to elevate your weeknight dinners. Make a batch, pair it with a crisp green salad or garlic bread, and enjoy the cozy, comforting meal you deserve. And if you want to keep exploring delicious chicken and Alfredo-based casseroles, check out the Baked Chicken Ziti Alfredo or the Cheesy Alfredo Chicken Pasta Casserole for more inspiration.

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