Measure and add the following to a small mixing bowl: 2 tablespoons chili powder, 2 tablespoons smoked paprika, 1 tablespoon garlic powder, 1 tablespoon onion powder, 1 tablespoon kosher salt, and 1 tablespoon cayenne pepper.
Stir or whisk the spices until the mixture is uniform in color and texture and there are no visible clumps.
Use a spoon or small funnel to transfer the seasoning mix into an airtight container.
Seal the container, label it (name and date), and store it in a cool, dry place away from direct heat or sunlight.
Use within 6 months for best flavor.