In a medium bowl, whisk together 1/2 cup soy sauce, 1/4 cup brown sugar, 4 pressed garlic cloves, 1 tablespoon minced ginger, 1 tablespoon sesame oil, 1 teaspoon garlic powder, 1 teaspoon onion powder, and 1/2 teaspoon crushed red pepper flakes until combined.
In a small bowl, stir 1 tablespoon cornstarch with 2 teaspoons water until smooth, then whisk this slurry into the sauce until fully incorporated.
Heat a large skillet over medium-high heat. Add 2 pounds ground beef and 1 diced onion. Cook, breaking the meat up with a spoon, until the beef is no longer pink and the onion is softened, about 6–8 minutes. If there is excess fat, drain or spoon off as needed.
Pour the prepared sauce into the skillet with the beef and onions and bring to a simmer, stirring to combine.
Reduce heat to medium and simmer, stirring occasionally, until the sauce thickens, about 5 minutes.
Remove from heat, sprinkle with 3 thinly sliced green onions, and serve.